This month (Jan 2015) Switzerland was the first country to launch Novo Nordisk’s Xultophy (IDegLira) for people with Type 2 diabetes. Xultophy is the first combination of a basal insulin (Tresiba, insulin degludec) and a GLP-1 analogue (Victoza, liraglutide). Xultophy is administered as a once-daily single injection independently of meals. It is intended for use in adults with Type 2 diabetes that are inadequately controlled with oral glucose-lowering treatments when these are used alone or together with basal insulin. For people with type 2 diabetes uncontrolled on basal insulin, Xultophy has demonstrated a significant 1.9% HbA1c reduction, mean weight loss of 2.7 kg and a low rate of hypoglycaemia (low blood sugar) comparable to insulin degludec. Novo Nordisk expects to make Xultophy available in other countries throughout Europe in 2015.
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